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Updated: Feb 20, 2026
07:11
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
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Factors Associated with Primary Open-angle Glaucoma in a Nepali Population: Jiri Eye Study
Summary
Primary open-angle glaucoma (POAG) is a leading cause of blindness. Early detection through screening strategies is crucial for preventing vision loss in at-risk populations.
Area of Science:
- Ophthalmology
- Public Health
- Genetics
Background:
- Glaucoma is the second leading cause of blindness globally.
- Primary open-angle glaucoma (POAG) is a significant contributor to vision impairment.
Purpose of the Study:
- To investigate ocular and systemic factors associated with the development of POAG.
- To inform early detection and screening strategies for POAG.
Main Methods:
- Population-based, analytical cross-sectional, oculo-genetic study.
- Included 2042 participants aged 18+, with 37 diagnosed with POAG.
- Comprehensive ophthalmic examinations and systemic assessments were performed.
Main Results:
- POAG prevalence was 2.53% in individuals aged 30+.
- Increased risk of POAG was observed in individuals aged 40+.
- POAG was significantly associated with elevated intraocular pressure, increased vertical cup disc ratio, and characteristic changes in retinal nerve fiber layer and visual field tests.
Conclusions:
- Identifying POAG-associated factors is key to developing effective screening programs.
- Early detection and intervention are vital for preventing blindness caused by POAG.
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