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Updated: Feb 20, 2026

Imine Metathesis by Silica-Supported Catalysts Using the Methodology of Surface Organometallic Chemistry
Published on: October 18, 2019
Metal-Free Intermolecular C-H Imidation of Anilines and Phenols With Sulfonimides
Koji Morimoto1,2, Kana Yanase1, Sana Kanemitsu1
1College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan.
None:
In this study, we developed a metal-free, intermolecular C(sp2)-H imidation of anilines and phenols using sulfonimides, yielding isolable aryl sulfonimides under facile conditions. MesI(OAc)2 and HNTs2 combine to produce an O-bridged I(III)-NTs2 adduct, which is stabilized via π-π stacking and aids efficient sulfonimide transfer. The necessary mild conditions and broad functional group tolerance of this transformation establish a sustainable C─N bond formation approach to synthesizing various aryl sulfonimides via hypervalent iodine-mediated C─H imidation.
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