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Maxillary Brown Tumor Unveiling Primary Hyperparathyroidism: A Rare Diagnostic Challenge
Abdur Rehman1, Haitham Akaash2, Javeria Awan2
1Department of ENT and Head and Neck Surgery Benazir Bhutto Hospital Rawalpindi Pakistan.
Clinical Case Reports
|February 19, 2026
Summary
Maxillary brown tumors can mimic other serious conditions. Early biochemical screening for primary hyperparathyroidism is crucial to prevent misdiagnosis of facial swelling.
Area of Science:
- Endocrinology
- Oral and Maxillofacial Surgery
- Oncology
Background:
- Maxillary brown tumors are rare entities.
- They can present diagnostic challenges due to their potential to mimic malignant or odontogenic lesions.
Purpose of the Study:
- To report a case of maxillary brown tumor as an initial manifestation of primary hyperparathyroidism.
- To emphasize the importance of biochemical screening in diagnosing such cases and avoiding misdiagnosis.
Main Methods:
- Case report presentation.
- Review of clinical presentation, diagnostic workup, and treatment outcomes.
- Emphasis on biochemical screening for primary hyperparathyroidism.
Main Results:
- Isolated facial swelling was the presenting symptom.
- Biochemical tests confirmed primary hyperparathyroidism.
- The maxillary brown tumor was linked to the underlying endocrine disorder.
Conclusions:
- Isolated facial swelling can be the first sign of primary hyperparathyroidism.
- Biochemical screening is essential for accurate diagnosis.
- Prompt diagnosis prevents misdiagnosis and unnecessary surgical interventions for maxillary brown tumors.

