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Related Experiment Video

Updated: Feb 21, 2026

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
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Association between left ventricular longitudinal function and left atrial strain in left ventricular dysfunction.

Björn Östenson1, Elsa Bergström1, Katarina Steding-Ehrenborg1

  • 1Clinical Physiology, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Entrégatan 7, 221 85, Lund, Sweden.

ESC Heart Failure
|February 19, 2026
PubMed
Summary
This summary is machine-generated.

Left atrial (LA) reservoir strain is significantly influenced by left ventricular (LV) longitudinal function in patients with LV dysfunction. Diminished LA strain may reflect underlying LV issues rather than being an independent cardiac marker.

Keywords:
Atrial functionAtrioventricular couplingCMRGlobal longitudinal strainVentricular function

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Area of Science:

  • Cardiology
  • Cardiac Imaging
  • Physiology

Background:

  • Left ventricular (LV) longitudinal function is a key prognostic indicator in LV dysfunction.
  • Left atrial (LA) reservoir and conduit strain are emerging prognostic markers.
  • The coupling between the atria and ventricles (LA-LV coupling) is crucial for cardiac function.

Purpose of the Study:

  • To quantify the association between LV longitudinal function and LA strain using cardiac magnetic resonance (CMR) feature-tracking.
  • To investigate if LA strain is determined by LV longitudinal function in LV dysfunction.

Main Methods:

  • Retrospective analysis of 342 patients with LV dysfunction and 19 healthy controls (HC).
  • Utilized CMR feature-tracking to analyze LV global longitudinal strain (LV-GLS), LV atrioventricular plane displacement (AVPD), and LA global longitudinal strain (LA-GLS).

Main Results:

  • LA-GLS was significantly lower in the LV dysfunction group compared to HC (12±8% vs 19±7, p<0.001).
  • Reductions in LA-GLS mirrored those in LV-GLS (-10±5% vs -19±3, p<0.001) and LV-AVPD (9±3 mm vs 15±2 mm, p<0.001).
  • A strong correlation was found between LV-GLS and LA-GLS (r²=0.40) and between LV-AVPD and LA-GLS (r²=0.39).

Conclusions:

  • LA reservoir function (LA-GLS) is largely determined by LV longitudinal function in patients with LV dysfunction.
  • LA function may not serve as an independent marker of global cardiac function in certain patient groups.
  • Diminished LA function can be a consequence of underlying LV dysfunction.