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Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness
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Enhancing LGBTQ+ Inclusivity in an AI-Powered Sexual Health Chatbot: User-Centered Design Approach Through a

William Wibowo Liem1, Elizabeth Casline1, Julianna Lorenzo1

  • 1Impact Institute, Northwestern University, Chicago, IL, United States.

Journal of Medical Internet Research
|February 19, 2026
PubMed
Summary

LGBTQ+ teenagers co-designed an AI chatbot for sexual health, improving inclusivity and trustworthiness. Their insights shaped content and features, demonstrating the value of involving marginalized youth in digital health tool development.

Keywords:
AILGBTQ+adolescentsartificial intelligencedigital healthinclusivitylesbian, gay, bisexual, transgender, and queersex educationsexual and gender minoritiessexual healthstakeholder participation

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Area of Science:

  • Digital Health
  • Artificial Intelligence
  • Sexual Health Education

Background:

  • Digital sexual health tools often exclude LGBTQ+ teenagers.
  • AI chatbots show promise but face bias and trust concerns.
  • Participatory design with marginalized youth is crucial for equitable digital health.

Purpose of the Study:

  • Examine LGBTQ+ teenagers' perceptions of the AI chatbot Roo.
  • Identify opportunities and challenges in delivering inclusive sexual health information.
  • Co-design improvements for AI-powered sexual health interventions.

Main Methods:

  • Collaborated with Planned Parenthood Federation of America (PPFA) to customize Roo.
  • Engaged a Youth Advisory Council of 15 LGBTQ+ teenagers.
  • Collected feedback via asynchronous Discord discussions and rapid qualitative analysis.

Main Results:

  • Teenagers expressed skepticism and curiosity about AI in sexual health.
  • Identified limitations in chatbot inclusivity, tone, and transgender-specific content.
  • Findings informed PPFA's updates to enhance content, reduce stigma, and improve transparency.

Conclusions:

  • Academic-nonprofit collaborations can enhance digital health tools using participatory methods.
  • LGBTQ+ teenagers acted as co-designers, shaping the chatbot's evolution.
  • Marginalized youth insights are vital for developing equitable AI health interventions.