What questions currently beyond reach do you hope systems approaches will enable addressing in the next decade?

Foundation model reveals the shared organization of transcription and topologically associating domains.

Cell systems·2026

Promera: a unified model for biomolecular structure prediction, filtering, and design.

bioRxiv : the preprint server for biology·2026

Thousandfold Expansion Microscopy.

bioRxiv : the preprint server for biology·2026

SwitchCraft: A Programmatic Framework for Designing State-Switching Proteins.

ArXiv·2026

Multi-resolution modeling of a discrete stochastic process identifies causes of cancer.

... International Conference on Learning Representations·2026

AI-based methods for simulating, sampling, and predicting protein ensembles.

Current opinion in structural biology·2026

Multiobjective learning and design of bacteriophage specificity.

Cell systems·2026

PROFET predicts continuous gene expression dynamics from scRNA-seq data to elucidate heterogeneity of cancer treatment responses.

Cell systems·2026

Ultrasensitive fitness costs arise from membrane proteome displacement under protein overexpression.

Cell systems·2026

Identifying memory gene expression from single-sample scRNA-seq data using power-law signatures.

Cell systems·2026

Single-cell transcriptional dynamics in a living vertebrate.

Cell systems·2026

Synthetic tissue ecology: Ecological control of developmental self-organization across scales.

Cell systems·2026

Insularity, character traits and local political interference: the pivotal players of the Sardinia regional health service's progressive decline.

Frontiers in public health·2026

Architecture and evolution of sleep during adult intensive care unit stay: A scoping review.

Sleep medicine·2026

Global Research Trends in ICU Nursing Personnel: A Bibliometric Analysis (2001-2025).

Journal of nursing management·2026

User-Centered Evaluation of Healthcare Information System Utilization: A Cross-Sectional Study Integrating Acceptance Models.

Health science reports·2026

Research Progress and Future Perspectives of Orexin Receptor Antagonists in Insomnia Therapy.

Molecules (Basel, Switzerland)·2026

Predicting ICU Delirium with a Regularized Logistic Regression Model: Device-Support Burden as an Informative Predictor Domain in a Turkish Cohort.

Diagnostics (Basel, Switzerland)·2026

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What questions currently beyond reach do you hope systems approaches will enable addressing in the next decade?

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Foundation model reveals the shared organization of transcription and topologically associating domains.

Promera: a unified model for biomolecular structure prediction, filtering, and design.

Thousandfold Expansion Microscopy.

SwitchCraft: A Programmatic Framework for Designing State-Switching Proteins.

Multi-resolution modeling of a discrete stochastic process identifies causes of cancer.

AI-based methods for simulating, sampling, and predicting protein ensembles.

Multiobjective learning and design of bacteriophage specificity.

PROFET predicts continuous gene expression dynamics from scRNA-seq data to elucidate heterogeneity of cancer treatment responses.

Ultrasensitive fitness costs arise from membrane proteome displacement under protein overexpression.

Identifying memory gene expression from single-sample scRNA-seq data using power-law signatures.

Single-cell transcriptional dynamics in a living vertebrate.

Synthetic tissue ecology: Ecological control of developmental self-organization across scales.

Insularity, character traits and local political interference: the pivotal players of the Sardinia regional health service's progressive decline.

Architecture and evolution of sleep during adult intensive care unit stay: A scoping review.

Global Research Trends in ICU Nursing Personnel: A Bibliometric Analysis (2001-2025).

User-Centered Evaluation of Healthcare Information System Utilization: A Cross-Sectional Study Integrating Acceptance Models.

Research Progress and Future Perspectives of Orexin Receptor Antagonists in Insomnia Therapy.

Predicting ICU Delirium with a Regularized Logistic Regression Model: Device-Support Burden as an Informative Predictor Domain in a Turkish Cohort.

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