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Candida auris Testing by the Antimicrobial Resistance Laboratory Network, United States, 2022-2023
Emerging Infectious Diseases
|February 19, 2026
Summary
Antimicrobial resistance in Candida auris is a major concern. In 2022-2023, 95% of tested Candida auris isolates in the US showed resistance to fluconazole, highlighting the need for better lab testing.
Area of Science:
- Clinical microbiology
- Infectious diseases
- Antimicrobial resistance
Background:
- Candida auris is an emerging multidrug-resistant fungal pathogen.
- Rising rates of Candida auris infections pose a significant public health challenge.
- Accurate laboratory identification and susceptibility testing are crucial for patient management.
Purpose of the Study:
- To assess the antifungal resistance patterns of clinical isolates of Candida auris in the United States.
- To evaluate the current landscape of Candida auris resistance to key antifungal agents.
Main Methods:
- The Antimicrobial Resistance Laboratory Network (ARLN) analyzed 8,033 clinical isolates of Candida auris.
- Antifungal susceptibility testing was performed for fluconazole, amphotericin B, and echinocandins.
Main Results:
- A high prevalence of fluconazole resistance (95%) was observed.
- Resistance to amphotericin B was noted in 15% of isolates.
- Echinocandin resistance was relatively low, affecting 1% of isolates.
Conclusions:
- Candida auris exhibits widespread resistance to fluconazole in the United States.
- Enhanced laboratory capacity for Candida auris identification and antifungal susceptibility testing is critical.
- Addressing this threat requires continued surveillance and improved diagnostic capabilities.
Keywords:
Candida aurisUnited Statesantimicrobial resistancecandidemiacross infectionfungiinfection controlMore Related Videos
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