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Related Concept Videos

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Related Experiment Video

Updated: Feb 21, 2026

Transmission of Multiple Signals through an Optical Fiber Using Wavefront Shaping
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Modelling light focusing via wavefront shaping under controlled dynamic scattering.

Mengjiao Zhang, Xuan Liu, Sebastien Ourselin

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    Summary
    This summary is machine-generated.

    Focusing light in dynamic biological tissues is challenging due to motion. This study introduces a simulation framework to understand and improve wavefront shaping for stable light delivery in scattering environments.

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    Area of Science:

    • Biomedical Optics
    • Light Propagation in Scattering Media

    Background:

    • Wavefront shaping aims to focus light through scattering media, but biological tissue dynamics cause temporal decorrelation, limiting its effectiveness.
    • Understanding and mitigating these dynamic effects is crucial for translating wavefront shaping to applications in living tissues.

    Purpose of the Study:

    • To develop and validate a simulation framework for modeling light propagation and wavefront shaping in temporally varying disordered media.
    • To analyze the impact of medium dynamics on wavefront shaping performance and identify strategies for stable light focusing.

    Main Methods:

    • An angular spectrum-based simulation framework was developed to model light propagation and wavefront shaping in dynamic scattering media.
    • The model allows independent control of phase perturbation magnitude and dynamic region extent to tune speckle decorrelation time and stable decorrelation level.
    • Simulations were validated against in vivo measurements from human tissue.

    Main Results:

    • The simulation framework accurately models decorrelation behavior in dynamic biological tissues.
    • Iterative, intensity-only characterization using the framework extracts the stable transmission component, enabling partial focus retention under dynamic conditions.
    • Decorrelation time and static correlation level were quantified as independent determinants of enhancement factor and post-optimization stability.

    Conclusions:

    • The developed simulation platform provides mechanistic insights into dynamic wavefront shaping in scattering media.
    • The findings offer practical guidance for optimizing light control in realistic, dynamic biological environments.
    • This work advances the potential for effective light delivery in biomedical applications involving scattering tissues.