A Rare Case of Prosthetic Joint Infection Caused by Group D Salmonella

Area of Science:

• Orthopedics
• Infectious Diseases
• Microbiology

Background:

• Prosthetic joint infections (PJIs) represent a significant healthcare challenge.
• Salmonella species are an uncommon cause of PJIs, with a predilection for hip over knee arthroplasty.
• Clinical data on managing knee PJIs caused by Salmonella is limited.

Purpose of the Study:

• To report a successful management of a rare case of knee PJI caused by Group D Salmonella.
• To emphasize the importance of tailored antibiotic therapy based on antimicrobial susceptibility.
• To highlight the necessity of multidisciplinary collaboration in managing complex PJIs.

Main Methods:

• A case of knee PJI caused by Group D Salmonella was identified.
• The patient underwent a two-stage revision surgery.
• Treatment included targeted antibiotic therapy guided by the isolate's antimicrobial susceptibility profile.

Main Results:

• Successful treatment outcome was achieved for the knee PJI.
• The two-stage revision surgery and appropriate antibiotic regimen were effective.
• The case underscores the feasibility of successful management despite the rarity of the causative agent.

Conclusions:

• Challenging PJIs, even those caused by rare pathogens like Salmonella, can be successfully managed.
• Effective treatment relies on a combination of appropriate surgical intervention and precise antibiotic therapy.
• Close collaboration between orthopedic surgeons and infectious disease specialists is crucial for optimal patient outcomes.