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Updated: Feb 21, 2026

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Published on: February 12, 2018
Predictive Factors for Macular Sensitivity and Fixation Stability After Pars Plana Vitrectomy for Rhegmatogenous
Abdullah H Al-Mulla1, Abdulrahman I Al-Souih1, Priscilla W Gikandi1
1Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Purpose:
To identify predictive factors for macular sensitivity and fixation stability following rhegmatogenous retinal detachment (RRD) repair using MP-1 microperimeter.
Methods:
Retrospective study of 66 eyes from 66 patients who underwent successful primary pars plana vitrectomy and had postoperative microperimetry assessment.
Results:
Median postoperative macular sensitivity was 12.9 decibels and median fixation stability was 81.5%. Median time between RRD repair and microperimetry testing was 10.0 months. Initial visual acuity ≥20/200 was associated with higher postoperative macular sensitivity (p=0.021) and fixation stability (p=0.004). Attached macula at presentation was associated with better macular sensitivity (p=0.041) and fixation stability (p=0.034). Gas tamponade resulted in superior outcomes compared to silicone oil for both macular sensitivity (p=0.004) and fixation stability (p<0.001). Multivariate regression analysis identified gas tamponade as the most significant predictor for better macular sensitivity (odds ratio = 5.53; 95% confidence interval [2.11-8.94]; p = 0.002). Significant negative correlations were observed between preoperative logarithm of the minimum angle of resolution (LogMAR) visual acuity and postoperative macular sensitivity (r=-0.253; p=0.043) and fixation stability (r=-0.408; p=0.001). Final LogMAR visual acuity was negatively correlated with macular sensitivity (r=-0.581; p<0.001) and fixation stability (r=-0.421; p<0.001).
Conclusion:
Better initial visual acuity, attached macula at presentation, and gas tamponade are significant predictors for better postoperative macular function after RRD repair.

