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Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
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Primary Indolent Acute Promyelocytic Leukemia.

Breanne Wolfenbarger1, Daley Morera2, Brandol Wolfenbarger2

  • 1Alabama College of Osteopathic Medicine, Dothan, AL 36303, USA.

Hematology Reports
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Summary

This case report details an unusual, slow-progressing acute promyelocytic leukemia (APL) with specific genetic mutations. Early diagnosis and treatment led to remission, expanding the understanding of APL presentations.

Area of Science:

  • Hematology
  • Oncology
  • Genetics

Background:

  • Acute promyelocytic leukemia (APL) is an aggressive myeloid leukemia subtype.
Keywords:
PML::RARAacute promyelocytic leukemiaindolent APL

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  • APL is defined by the PML::RARA fusion gene and often presents with severe coagulopathy.
  • Prompt diagnosis and treatment are critical due to the disease's typically rapid progression.