Related Experiment Video
Updated: Feb 22, 2026
09:55
Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology
Published on: September 28, 2022
2.3K
Sustaining grant-funded programs: Conditions for sustaining initiatives that enhance diversity in STEMM
Naomi A Stephen1, Krystle P Cobian2, Ana L Romero1
1School of Education and Information Studies, University of California, Los Angeles, California, United States of America.
Plos One
|February 20, 2026
Summary
This study identified key interventions like undergraduate research training and faculty mentoring that promote sustainable diversity in science, technology, engineering, mathematics, and medicine (STEMM) workforce programs. Institutional support and alignment with priorities were crucial for long-term success.
Area of Science:
- Biomedical Sciences
- Higher Education
- Workforce Development
Background:
- Funding agencies increasingly require sustainable institutional change for STEMM workforce diversity.
- Little is known about which STEMM interventions are most likely to be sustained beyond grant funding.
Purpose of the Study:
- To examine the sustainability of interventions within the NIH BUilding Infrastructure Leading to Diversity (BUILD) initiative.
- To identify factors facilitating the sustainability of biomedical workforce diversity programs.
Main Methods:
- A multiple case study design was employed.
- Examined 10 higher education sites participating in the NIH BUILD initiative over a 10-year award period.
Main Results:
- Undergraduate research training, faculty mentoring training, and curricular changes were the most sustainable interventions.
- Four contextual elements facilitated sustainability: financial status, infrastructure/partnerships, administrative/faculty commitment, and alignment with institutional priorities.
Conclusions:
- Specific interventions and supportive contextual factors are key to sustaining institutional change for STEMM diversity.
- Provides actionable insights for grant-funded teams and administrators aiming to enhance equity and inclusion in STEMM.
Related Concept Videos
01:22Diversity in Cell Signaling Responses
8.0K
The physiological function of a cell and cellular communication are outcomes of a range of extrinsic signals, intracellular signaling pathways, and cellular responses. No two cell types express the same repertoire of signaling components. Receptors are highly selective for their cognate ligands, but once activated, they can alter multiple cellular processes such as DNA transcription, protein synthesis, and metabolic activity.
Graded and Abrupt Responses
Some signaling systems generate...
Graded and Abrupt Responses
Some signaling systems generate...
8.0K
01:26Stem Cell Niche
6.4K
The stem cell niche is the dynamic microenvironment where stem cells reside. Inside these niches, the cells may remain undifferentiated, undergo high self-renewal, or become lineage-specific progenitors. Stem cells coexist with other niche cells, such as stromal cells. They also interact closely with the ECM. Cell-cell and cell-matrix communication occur via adhesion molecules or soluble factors that signal the stem cells and determine their fate. Stromal cells also provide survival signals to...
6.4K
01:17Stem Cell Culture
6.2K
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
6.2K
01:01Regulation of Hematopoietic Stem Cells
4.2K
All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a limited life span. In addition, many are depleted in immune surveillance or combatting an injury or infection. This makes blood one of the most regenerative tissues. Hematopoiesis helps replenish these blood and immune cells, restoring the body's normal functioning. However, overproduction of blood and immune cells can make them cancerous or...
4.2K
01:19Multipotency of Hematopoietic Stem Cells
4.0K
The hematopoietic stem cells or HSCs are multipotent, meaning they can differentiate and give rise to all blood and immune cells. HSCs are maintained in the quiescent stage until an external stimulus initiates their differentiation. The multipotent HSCs exist as two heterogeneous populations, long-term repopulating cells (LTRC) and short-term repopulating cells (STRC). The two HSC populations have different surface markers or receptors and are classified based on quiescence and long-term...
4.0K
01:06Multipotency and Niche of Bulge Stem Cell
4.3K
A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
4.3K