The meaning of life in a universe whose ultimate origins are unknown

Our universe appears to be fine-tuned for life. But once life emerges, it does not evolve randomly. Evolution has a trajectory. Both evolvability and cooperative integration increase as evolution proceeds. Until now, this trajectory has largely been driven blindly by gene-based natural selection. But humans are developing cognitive capacities that are far superior than natural selection at adapting and evolving humanity. These capacities will enable humanity to use an understanding of evolution's future trajectory to guide its own evolution, avoiding the destructive selection that will otherwise reinforce the trajectory. Humans who help realize this potential will be fulfilling vital evolutionary roles that are meaningful and purposeful in a much larger scheme of things. The paper considers whether these roles remain meaningful when considered in the wider context of possible origins of the universe. But this analysis is faced with a potentially infinite number of origin hypotheses (including innumerable 'God hypotheses'), which are not falsified by current knowledge. The paper addresses this challenge using methods that enable rational decision-making despite radical uncertainty. Broadly, this approach reinforces the conclusions reached by consideration of the evolutionary trajectory within the universe, and opens some new possibilities. Finally, the paper demonstrates that extending this analysis also largely overcomes Hume's critique of induction, placing scientific methodologies on a firmer footing. It achieves this by recognising that a universe which exhibits a trajectory towards increasing evolvability must contain discoverable regularities that provide adaptive advantages for evolvability.