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Updated: Feb 22, 2026

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

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Fatigue Resistant Hydrogels Engineered With Twisting Hierarchical Structures.

Yinghui Feng^1,2, Yafei Wang¹, Chang Wang¹

¹Department of Mechanical and Energy Engineering, Southern University of Science and Technology, Shenzhen, China.

Advanced Materials (Deerfield Beach, Fla.)

|February 21, 2026

Summary

This summary is machine-generated.

Researchers developed a bioinspired twisting method to significantly improve hydrogel durability for soft robotics and biomedical uses. This strategy enhances mechanical strength and fatigue resistance, overcoming key limitations for dynamic applications.

Keywords:

bioinspired fatigue resistance hierarchical structure hydrogels twisting

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Area of Science:

Materials Science
Robotics
Biomedical Engineering

Background:

Hydrogels offer biocompatibility and softness for soft robotics and biomedical applications.
Poor fatigue resistance limits hydrogel utility in dynamic, long-term loading scenarios.

Purpose of the Study:

To enhance the mechanical durability and fatigue resistance of hydrogel materials.
To develop a bioinspired twisting strategy for improved hydrogel performance.

Main Methods:

A bioinspired torsion methodology was applied to hydrogel fibers.
Multiscale simulations were used to analyze stress distribution under twisting.
Proof-of-concept demonstrations included a frog-tongue-inspired actuator.

Main Results:

The twisting strategy significantly improved tensile strength, stretchability, and fatigue thresholds.
Moderate twisting promoted uniform stress distribution, while excessive twisting led to geometric locking.
The hydrogel fibers maintained structural integrity during prolonged cycling.

Conclusions:

The bioinspired twisting approach provides a universal design paradigm for fatigue-resistant hydrogel systems.
This method enhances hydrogel performance for demanding applications in implantable medical devices and soft robotics.
The strategy is compatible with various hydrogel systems, including PVA, alginate, and cellulose composites.