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Updated: Feb 22, 2026

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Elucidating the role of the T790M mutation in BLU-945 selectivity for mutant EGFR: structural and energetic insights

Amina Tariq1, Muhammad Shoaib1, Lingbo Qu1,2

  • 1College of Chemistry, Pingyuan Laboratory, and State Key Laboratory of Cotton Bio-breeding and Integrated Utilization, Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.

Journal of Computer-Aided Molecular Design
|February 21, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Conformational dynamicsDrug resistanceEGFR inhibitorFree energy landscapesMolecular dynamics

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