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Complicating the Crisis: Superinfection in Covid 19 Patients
Sonali Maheshwari1, Subhashree Mohapatra2, Vikas Dogra3
1Department of Microbiology, Institute of Human Behaviour and Allied Sciences, New Delhi, India.
Background:
Pulmonary diseases of viral origin are often followed by the manifestation of secondary infections, leading to further clinical complications. Understanding its characteristics is of great significance in Covid 19. Nevertheless, there is little data regarding bacterial superinfection and its risk factors in COVID-19 patients who are critically ill.
Aims:
The aim of this study was to assess the extent of superinfections caused by various microorganisms in severe acute respiratory syndrome coronavirus 2-infected inpatients and to evaluate the risk factors for superinfection.
Methods:
The Study was conducted from October to January 2021 at a COVID-19 dedicated, a large tertiary care hospital of North India. Nasopharyngeal swabs were collected and processed for SARS-CoV 2 by reverse transcription-polymerase chain reaction. To diagnose superinfections, appropriate samples were collected from the patients and processed for isolation of bacterial and fungal microorganisms based on the judgment of the treating physician.
Results:
The rate of super-infections found during our study period was 7.69.
Conclusion:
In our study, we identified Severe COVID-19, previous antibiotic use, and invasive therapy as the three risk factors of overall superinfections.
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