Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Infection01:20

Infection

12.9K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
12.9K
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

14.1K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
14.1K
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

6.0K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
6.0K
Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

3.1K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
3.1K
Gene Regulation in Microbial Communities: Quorum Sensing01:28

Gene Regulation in Microbial Communities: Quorum Sensing

752
Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
752
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

593
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
593

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An Optimized Protocol for Candida albicans Infection in Schmidtea mediterranea to Study Fungal Pathogenesis and Host Defense.

Journal of visualized experiments : JoVE·2026
Same author

Transcriptomic characterization of Coccidioides morphological states using RiboMarker-enhanced RNA sequencing.

G3 (Bethesda, Md.)·2026
Same author

Global emergence and rapid spread of <i>Candidozyma auris</i> (syn. <i>Candida auris</i>): epidemiology, biology, and antifungal resistance.

Clinical microbiology reviews·2026
Same author

Lem3, a phospholipid flippase subunit, influences <i>Candida albicans</i> pathogenicity through maintenance of plasma membrane asymmetry.

Microbiology spectrum·2026
Same author

Correction: The emerging pathogen Candida auris: host interactions and disease drivers.

Journal of biomedical science·2026
Same author

A review of the venom microbiome and its utility in ecology and evolution including future directions for emerging research.

Symbiosis (Philadelphia, Pa.)·2026

Related Experiment Video

Updated: Feb 23, 2026

Studying Microbial Communities In Vivo: A Model of Host-mediated Interaction Between Candida Albicans and Pseudomonas Aeruginosa in the Airways
06:43

Studying Microbial Communities In Vivo: A Model of Host-mediated Interaction Between Candida Albicans and Pseudomonas Aeruginosa in the Airways

Published on: January 13, 2016

9.5K

The emerging pathogen Candida auris: host interactions and disease drivers.

Daniel Ruben Akiola Sanya1, Ashley Valle Arevalo2, Djamila Onésime3

  • 1INRAE, AgroParisTech, Micalis Institute, Université Paris-Saclay, 78350, Jouy-en-Josas, France. daniel.sanya36@gmail.com.

Journal of Biomedical Science
|February 21, 2026
PubMed
Summary

Candida auris is a multidrug-resistant fungus causing dangerous hospital infections. New strategies are needed for its diagnosis, treatment, and prevention to combat this emerging pathogen.

Keywords:
Candida aurisAntifungal agentsAntimicrobial resistanceCellular microbiologyClinical microbiologyDiagnostic markersFungal infectionFungiPathogens

More Related Videos

Author Spotlight: Enhancing Candida albicans Detection in Catheter Infections Using Fluorescent Protein Tagging
03:24

Author Spotlight: Enhancing Candida albicans Detection in Catheter Infections Using Fluorescent Protein Tagging

Published on: March 22, 2024

2.2K
Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis
08:48

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis

Published on: March 19, 2019

7.5K

Related Experiment Videos

Last Updated: Feb 23, 2026

Studying Microbial Communities In Vivo: A Model of Host-mediated Interaction Between Candida Albicans and Pseudomonas Aeruginosa in the Airways
06:43

Studying Microbial Communities In Vivo: A Model of Host-mediated Interaction Between Candida Albicans and Pseudomonas Aeruginosa in the Airways

Published on: January 13, 2016

9.5K
Author Spotlight: Enhancing Candida albicans Detection in Catheter Infections Using Fluorescent Protein Tagging
03:24

Author Spotlight: Enhancing Candida albicans Detection in Catheter Infections Using Fluorescent Protein Tagging

Published on: March 22, 2024

2.2K
Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis
08:48

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis

Published on: March 19, 2019

7.5K

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Antimicrobial Resistance

Background:

  • Candida auris is a multidrug-resistant fungal pathogen causing hospital-acquired infections with high mortality.
  • Clinical isolates show resistance to antifungal drugs, complicating treatment.
  • Challenges include persistent colonization, biofilm formation, and diagnostic misidentification.

Purpose of the Study:

  • To summarize the clinical spectrum of Candida auris infections.
  • To highlight key pathogenic traits and clade-specific differences.
  • To discuss emerging strategies for diagnosis, therapy, and prevention.

Main Methods:

  • Literature review and synthesis of current knowledge on Candida auris.
  • Analysis of clinical data and pathogenic characteristics.
  • Exploration of novel diagnostic, therapeutic, and preventative approaches.

Main Results:

  • Candida auris infections present a significant global health threat due to multidrug resistance.
  • Pathogenic traits and clade variations influence disease presentation and treatment outcomes.
  • Emerging strategies show promise for improved detection and management.

Conclusions:

  • Effective patient care and infection control necessitate rapid species identification and antifungal susceptibility testing.
  • Novel antifungal agents, host-directed therapies, and vaccine development are crucial for future interventions.
  • Addressing the challenges posed by Candida auris requires a multifaceted approach encompassing diagnostics, therapeutics, and prevention.