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A new inducible mouse model of FH loss
Vincent Zecchini1, Chrysanthi Moschandrea2, Farina Schneider2
1MRC Cancer Unit, Hutchison-MRC Research Institute, University of Cambridge, Cambridge, United Kingdom.
Methods in Cell Biology
|February 22, 2026
Abstract:
Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) is a rare autosomal dominant disorder that is characterized by the development of multiple cutaneous and uterine leiomyomas and predisposes individuals to an aggressive and highly metastatic form of Renal Cell Cancer (RCC).
