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Updated: Feb 24, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
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Transient Ventricular Capture Loss Following Alcohol Septal Ablation in Left Bundle Branch Area Pacing: A Case Report

Chia-Hao Liu1, Jing-Han Yao1, Chia-Hao Chen1

  • 1Division of Cardiovascular Medicine, Department of Medicine, China Medical University Hospital, Taichung, Taiwan.

Journal of Cardiovascular Electrophysiology
|February 23, 2026
PubMed

Insights

Alcohol septal ablation (ASA) may temporarily affect left bundle branch area pacing (LBBAP) capture if the ablation zone is near the lead. Careful imaging and backup pacing are recommended during ASA procedures.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Interventional Cardiology

Background:

  • Alcohol septal ablation (ASA) is a standard treatment for symptomatic hypertrophic obstructive cardiomyopathy (HOCM).
  • ASA can lead to conduction abnormalities.
  • Limited data exist on the interaction between ASA and left bundle branch area pacing (LBBAP) leads.
Abstract

Keywords:
alcohol septal ablationlead dysfunctionleft bundle branch area pacingleft ventricular outflow tract obstruction

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