Impact of Yoga Practice on Inflammatory Markers and Stress Levels

Yoga is increasingly incorporated into clinical practice for managing a wide range of mental and physical health conditions, especially those related to stress, and has shown beneficial effects on inflammatory processes and neuroendocrine regulation. Its influence on cytokines such as interleukin-6 and tumor necrosis factor-α, as well as its modulatory action on the hypothalamic pituitary adrenal axis, suggests a potential role in reducing systemic inflammation and improving stress resilience. Despite these promising indications, there is limited scientific evidence from India evaluating yoga's impact on biological markers of stress and inflammation. The present study was undertaken to assess the effects of a structured yoga program on selected biomarkers in 60 adult volunteers who underwent evaluations before and after 3 months of practice. The intervention consisted of a daily 1-h yoga session conducted 6 days a week and included postures, breathing practices, and relaxation techniques. Assessments focused on brain-derived neurotrophic factor, interleukin-6, tumor necrosis factor-α, high-sensitivity C-reactive protein, cortisol, and perceived stress levels. Findings indicated an increase in brain-derived neurotrophic factor and reductions in inflammatory markers, cortisol, and perceived stress. These outcomes suggest that regular yoga practice can positively influence neurotrophic activity, reduce inflammation, and lower stress, supporting its value as a complementary approach to improving overall health and well-being.