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Updated: Feb 24, 2026

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Author Spotlight: Exploring Peripheral Mechanisms of Neuropathic Pain in Trigeminal Nerve Injury
Published on: February 9, 2024
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Trigeminal trophic syndrome
Kavyadeepu R M1, Mohnish Sekar2
1Department of Dermatology, Chettinad Hospital and Research Institute, Kelambakkam, Tamil Nadu, India.
Dermatology Online Journal
|February 23, 2026
Summary
Trigeminal trophic syndrome (TTS) is a rare nerve injury causing facial numbness, altered sensation, and ulcers. This case highlights TTS following herpes zoster infection, emphasizing neurotrophic factors in its development.
Area of Science:
- Neurology
- Dermatology
- Ophthalmology
Background:
- Trigeminal trophic syndrome (TTS) is a rare condition resulting from trigeminal nerve damage.
- It classically presents with unilateral facial anesthesia, paresthesia, and ulceration.
- While iatrogenic injury is common, other causes include stroke, trauma, tumors, infections, and degenerative diseases.
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