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Updated: Feb 24, 2026

Implantation of Left Ventricular Assist Device (LVAD) in Juvenile Landrace Swine: A LVAD Implantation Model of Pediatric Heart Failure
Published on: January 16, 2026
Challenges in managing pediatric heart failure, especially in resource-limited settings
Lamk Kadiyani1, Sivasubramanian Ramakrishnan1
1Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India.
Pediatric heart failure (HF) management requires tailored approaches due to unique pathophysiology and limited pediatric data. More large-scale trials are crucial for optimizing treatment strategies in children globally.
Area of Science:
- Pediatric Cardiology
- Cardiovascular Research
- Translational Medicine
Background:
- Pediatric heart failure (HF) presents distinct global epidemiological profiles, differing from adult HF.
- Congenital heart disease and cardiomyopathies are prevalent in developed nations, while rheumatic heart disease dominates in low- and middle-income countries.
- Pediatric HF pathophysiology, including cardiac physiology, molecular signaling, and ventricular remodeling, is unique compared to adults.
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