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H2O2‑Responsive Organic Small-Molecule MRI Probes for Acute Kidney Injury Imaging and Detection

Rulong Chen1,2, Shangpo Yang3,4, Duyang Gao3

  • 1Department of Nephrology, The People's Hospital of Baoan Shenzhen, The Second Affiliated Hospital of Shenzhen University, Shenzhen Hospital of Guangdong Provincial People's Hospital, the Affiliated Baoan Hospital of Southern Medical University, Shenzhen Baoan Clinical Medical School of Guangdong Medical University, The Eighth people's Hospital of Shenzhen, Baoan Clinical Research Center for Kidney Disease, Shenzhen, 518000, PR China.

ACS Omega
|February 23, 2026
PubMed
Summary

Researchers developed novel organic radical MRI contrast agents for acute kidney injury (AKI) detection. These agents offer redox-responsive signals and rapid renal clearance, avoiding traditional contrast agent risks.

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