Related Experiment Video
Updated: Feb 24, 2026

Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice
Published on: February 1, 2022
Successful Management of Contained Left Ventricular Free Wall Rupture Associated With Myocardial Infarction
Mojtaba Mansouri1, Fatemeh Jadidi2, Abbas Toughanipour1
1Department of Anesthesiology, School of Medicine, Anesthesiology and Critical Care Research Center, Chamran Hospital Isfahan University of Medical Science Isfahan Iran.
Abstract:
Left ventricular free wall rupture (LVFWR) is a deadly mechanical complication that, in approximately 2%-6% of patients, arises following acute myocardial infarction (MI). It could occur in different situations, ranging from several minutes to over one month following MI, usually among patients with risk factors. The condition is very lethal, and the survival rates are extremely low among the people affected. We here report the case of a 61-year-old female patient presenting with chest discomfort and dyspnea two months after an anterior MI. In this case, unlike most instances, the visceral pericardium acts as a protective layer, preventing further bleeding and progression toward tamponade. Furthermore, prompt surgery was crucial in preventing fatal outcomes and ended up saving the patient's life.
Insights
Left ventricular free wall rupture (LVFWR) is a rare but fatal complication after myocardial infarction (MI). This case highlights the protective role of the pericardium and the critical importance of prompt surgical intervention for survival.
Area of Science:
- Cardiology
- Cardiac Surgery
- Pathophysiology
Background:
- Left ventricular free wall rupture (LVFWR) is a severe mechanical complication following acute myocardial infarction (MI).
- LVFWR occurs in 2%-6% of MI patients, often weeks to months post-MI, and carries a very high mortality rate.
- Risk factors and typical presentations of LVFWR are well-documented, but atypical cases offer valuable learning opportunities.
Purpose of the Study:
- To report a unique case of LVFWR presenting two months after anterior MI.
- To illustrate the potential protective role of the visceral pericardium in preventing catastrophic hemorrhage and tamponade.
- To emphasize the life-saving impact of timely surgical repair in managing LVFWR.
Main Methods:
- Case report of a 61-year-old female patient with delayed presentation of LVFWR post-MI.
- Clinical evaluation including assessment of chest discomfort and dyspnea.
- Surgical intervention for LVFWR repair.
Main Results:
- The patient presented with symptoms two months after an anterior MI, indicative of LVFWR.
- The visceral pericardium appeared to contain the rupture, preventing immediate tamponade.
- Prompt surgical repair successfully managed the LVFWR, leading to a positive outcome.
Conclusions:
- This case underscores that LVFWR can present atypically, even months after MI.
- The pericardium may play a crucial role in limiting bleeding in some LVFWR cases.
- Urgent surgical management remains paramount for improving survival rates in patients with LVFWR.
Related Concept Videos
Myocarditis III: Medical Management
Acute Coronary Syndrome IV: Interprofessional Care
Pericarditis III: Medical Management
Mitral Stenosis III: Medical Management
Aortic Regurgitation III: Medical Management
Cardiomyopathy VII: Pre and Post Operative Nursing Management

