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The Effect of N-Alkyl Azole Difluorination on Molecular Properties Relevant for Compound Optimization: A Comparative

Ryan M Herrick1, Samantha A Green2, Sharyl Rich2

  • 1Borch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA.

ACS Medicinal Chemistry Letters
|February 23, 2026
PubMed
Abstract

Keywords:
DIFLUORINATIONFLUORINATIONHETEROCYCLESMATCHED MOLECULAR PAIRS

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