Related Experiment Video
Updated: Feb 25, 2026

Insulin Injection and Hemolymph Extraction to Measure Insulin Sensitivity in Adult Drosophila melanogaster
Published on: June 30, 2011
[Characteristics and methods of use of insulins]
1Service d'endocrinologie et diabétologie, hôpital Lapeyronie, Montpellier, France.
Abstract:
Life-saving for people with type 1 or insulin-deprived diabetes for other causes, needed for people with type 2 diabetes or diabetes of other origin for which glucose control is not achievable without it, insulin therapy has shown a dramatic evolution during the last 30 years. The multiple-daily insulin injection regimens almost only use fast-acting and long-acting insulin analogues, according to a standard-of-care basal-bolus scheme. The initiation of insulin therapy in type 2 diabetes electively promotes the use of a long-acting insulin analogue. Using premix combinations of a fast-acting analogue and NPH insulin becomes obsolete. The treatment by insulin pumps which uses only fast-acting analogues has shown a major development in type 1 diabetes, amplified during the recent 5 years by the availability of automated insulin delivery systems.
Related Concept Videos
Insulin Formulations: Types and Delivery
Short-acting insulins are divided into...
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Insulin: Biosynthesis, Chemistry, and Preparation
Damage or functional impairment of β-cells inhibits insulin production, leading to diabetes. Diabetes treatment...
Oral Hypoglycemic Agents: Glinides
Oral Hypoglycemic Agents: Sulfonylureas
Glucagon-like Receptor Agonists
GLP-1, when administered in high doses intravenously, triggers insulin secretion, inhibits glucagon release, slows gastric emptying, reduces food intake, and restores normal insulin secretion. However, its rapid inactivation by...

