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Assessing Lisfranc Instability With Triplanar Weightbearing CT Alignment: Standardized Second Metatarsal Dorsal
Wolfram Grün1,2,3, Pierre-Henri Vermorel1,4,5, Emily J Luo1
1Department of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC, USA.
Foot & Ankle Orthopaedics
|February 24, 2026
Summary
Subtle Lisfranc injuries are hard to detect. Weightbearing CT (WBCT) and a new measurement, second metatarsal dorsal offset (M2DO), improve detection of Lisfranc instability.
Area of Science:
- Orthopedic surgery
- Radiology
- Biomechanics
Background:
- Subtle Lisfranc injuries often go undetected with conventional imaging.
- Weightbearing computed tomography (WBCT) provides 3D assessment under load, potentially improving instability detection.
- The interval between the medial cuneiform (C1) and second metatarsal (M2) is a common measurement, but sagittal displacement may offer additional diagnostic value.
Purpose of the Study:
- To evaluate the reliability and diagnostic utility of a new WBCT measurement, second metatarsal dorsal offset (M2DO), for detecting Lisfranc instability.
- To compare M2DO measurements between injured and uninjured feet.
- To assess the intra- and interobserver reliability of the M2DO measurement.
Main Methods:
- Retrospective analysis of 31 patients with acute Lisfranc injuries who underwent bilateral WBCT.
- Standardized measurement of M2DO following triplanar alignment of the second metatarsal (M2) relative to the second cuneiform (C2).
- Independent measurements by two foot and ankle surgeons, with one repeating measurements after two weeks to assess reliability.
Main Results:
- M2DO showed a significant difference between injured (0.71 ± 1.18 mm) and uninjured feet (-0.74 ± 0.66 mm) (P < .0001).
- Intra- and interobserver reliability for M2DO was almost perfect in injured feet (intrarater 0.92, interrater 0.94) and the overall cohort (0.93, 0.92).
- Substantial reliability was observed in uninjured feet (intrarater 0.79, interrater 0.67).
Conclusions:
- Second metatarsal dorsal offset (M2DO) is a reliable parameter derived from WBCT for assessing Lisfranc instability.
- M2DO may complement existing C1-M2 measurements, enhancing diagnostic accuracy and reproducibility.
- Further research is needed to establish M2DO thresholds for surgical decision-making and clinical application.

