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Updated: Feb 25, 2026
A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Five new cassane diterpenoids from the seeds of Pterolobium macropterum
Yi-Hui Li1, Gang Ke2, Yue-Ping Lan3
1College of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang330004, China.
Abstract:
Five undescribed cassane diterpenoids were obtained from the seeds of Pterolobium macropterum. Their structures were established through extensive 1D and 2D NMR spectroscopy, and mass spectrometry. Their absolute configurations were assigned by electronic circular dichroism spectrum. Compounds 1 and 3 exhibited cytotoxic effects for the human glioma U251 cells with IC50 values of 28.48 ± 2.7 and 14.43 ± 7.8 μM, respectively.
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