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Updated: Feb 26, 2026

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VIPR1 acts as an enteric neural checkpoint that suppresses intestinal stem cell-driven epithelial regeneration and

Chaoliang Li1, Haohao Wang1, Panrui Zhang2

  • 1Department of Digestive Disease, The First Affiliated Hospital of USTC, State Key Laboratory of Immune Response and Immunotherapy, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China; Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China.

Cell Stem Cell
|February 24, 2026
PubMed
Abstract

Keywords:
NotumWNT signalingepithelial regenerationgut-innervating neuronsinflammatory bowel diseaseintestinal stem cellsneuron-epithelial interaction

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