Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Phases of Wound Repair01:28

Phases of Wound Repair

9.1K
Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
9.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rational design of ultra-inert Gd-DOTABA probes conjugated with unnatural dipeptides for high-contrast and low-dose tumor and vascular MRI.

European journal of medicinal chemistry·2026
Same author

Three-dimensional printed artificial vertebral body versus titanium mesh cage and nanohydroxyapatite/polyamide-66 cage in anterior cervical corpectomy and fusion: a retrospective cohort study with a minimum 5-year follow-up.

Journal of orthopaedic surgery and research·2026
Same author

A Disulfide-Sticker Strategy for Marine Adhesive Coatings: From Deciphering Self-Assembly Mechanism to Functional Application in Hair Regeneration.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

A Self-Immunoregulatory Nanosensitizer for Sonodynamic Cancer Therapy.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Inhibitory effect of Acetylshikonin on drug-resistant Candida albicans.

Gut pathogens·2026
Same author

A Self-Cascading Immunomodulatory Hydrogel for Remodeling Infected Diabetic Wounds.

Advanced materials (Deerfield Beach, Fla.)·2026

Related Experiment Video

Updated: Feb 26, 2026

Engineering a Bilayered Hydrogel to Control ASC Differentiation
07:48

Engineering a Bilayered Hydrogel to Control ASC Differentiation

Published on: May 25, 2012

14.5K

Self-assembled hydrogels promote wound healing.

Da Lin1,2, Yanqiang Huang3,4, Yuna Qian5,6

  • 1Youjiang Medical University for Nationalities, Baise, Guangxi 533000, China. why-825@163.com.

Journal of Materials Chemistry. B
|February 25, 2026
PubMed
Summary

Self-assembled hydrogels offer advanced wound healing by mimicking the dynamic wound environment. These materials provide structural support and exhibit antimicrobial, anti-inflammatory, and antioxidant properties for improved tissue repair.

More Related Videos

Author Spotlight: Improving the Production of Self-Assembling Fibers and Peptide Hydrogels for Superior Biocompatibility
05:24

Author Spotlight: Improving the Production of Self-Assembling Fibers and Peptide Hydrogels for Superior Biocompatibility

Published on: September 6, 2024

1.7K
Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture
08:05

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture

Published on: September 29, 2017

20.1K

Related Experiment Videos

Last Updated: Feb 26, 2026

Engineering a Bilayered Hydrogel to Control ASC Differentiation
07:48

Engineering a Bilayered Hydrogel to Control ASC Differentiation

Published on: May 25, 2012

14.5K
Author Spotlight: Improving the Production of Self-Assembling Fibers and Peptide Hydrogels for Superior Biocompatibility
05:24

Author Spotlight: Improving the Production of Self-Assembling Fibers and Peptide Hydrogels for Superior Biocompatibility

Published on: September 6, 2024

1.7K
Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture
08:05

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture

Published on: September 29, 2017

20.1K

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Tissue Engineering

Background:

  • Wound healing is a complex biological process involving inflammation, proliferation, and remodeling.
  • Chronic conditions like infections and diabetes impair wound repair, necessitating novel therapeutic strategies.
  • Conventional treatments often fail to address the multifaceted nature of the wound microenvironment.

Purpose of the Study:

  • To review recent advancements in self-assembled hydrogels for wound healing applications.
  • To elucidate the mechanisms of action of self-assembled hydrogels in promoting tissue repair.
  • To highlight the potential of these innovative materials in overcoming limitations of conventional therapies.

Main Methods:

  • Review of current literature on self-assembled hydrogels in wound management.
  • Analysis of the unique properties of self-assembled hydrogels, including spontaneous network formation and dynamic features.
  • Evaluation of the biological activities demonstrated by these hydrogels, such as antimicrobial, anti-inflammatory, and antioxidant effects.

Main Results:

  • Self-assembled hydrogels form 3D networks without external crosslinkers or energy input.
  • These hydrogels exhibit dynamic properties like reversibility, self-healing, and stimulus responsiveness, suiting dynamic wound environments.
  • Multifaceted biological activities enhance their therapeutic potential beyond structural support.

Conclusions:

  • Self-assembled hydrogels represent a promising innovative strategy for effective wound repair.
  • Their unique properties and biological activities address limitations of conventional wound management approaches.
  • Further understanding of their mechanisms can accelerate the development of advanced wound healing therapies.