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E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

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A Co-Design Study Developing an Early Prototype Intervention to Support Oral Anticancer Medication Use in Breast

Yejin Seo¹, Karen Suchanek Hudmon¹, Kellie Jones Weddle¹

¹College of Pharmacy, Purdue University, West Lafayette, IN, USA.

Patient Preference and Adherence

|February 25, 2026

Summary

Patients co-designed interventions for managing oral anticancer medications (OAMs) for breast cancer. Prototypes include a handbook and app to improve OAM adherence and patient support.

Keywords:

breast cancer medication adherence medication management participatory design patient centered outcomes

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Area of Science:

Oncology
Patient-centered care
Health informatics

Background:

Breast cancer is a leading cause of death in women.
Oral anticancer medications (OAMs) increase patient responsibility for management.
Inadequate patient support for OAMs is a growing concern.

Purpose of the Study:

To co-design an early-stage intervention prototype.
To support breast cancer patients managing OAMs.
Utilize a patient-centered, participatory design approach.

Main Methods:

Conducted participatory design (PD) sessions with five breast cancer patients on OAMs.
PD involved inspiration, ideation, and convergence stages.
Patients identified challenges and co-developed solutions.

Main Results:

Key challenges included side-effect management and resource navigation.
Ten solutions were generated, leading to two priority prototypes: a handbook and a navigation app.
Patients favored the handbook's usability and the app's communication features.

Conclusions:

Engaging patients as co-designers is valuable for intervention development.
Both handbook and app prototypes show potential for improving OAM adherence.
Findings offer insights for future oral anticancer medication support interventions.