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Potential clinical impact of pharmaceutical interventions in an interprofessional medication management program

Christiane Eickhoff1, Ann Kathrin Strunz1, Maike Petersen1

  • 1Department of Medicine, ABDA - Federal Union of German Associations of Pharmacists, Berlin, Germany.

Exploratory Research in Clinical and Social Pharmacy
|February 25, 2026
PubMed
Abstract

Insights

The ARMIN program, combining medication reviews and continuous management, reduced mortality risk by addressing drug-related problems through pharmaceutical interventions. Effective collaboration between community pharmacists and physicians was key to successful medication management.

Area of Science:

  • Pharmaceutical care
  • Medication safety
  • Health services research

Background:

  • Medication reviews (MR) and continuous medication management (MM) enhance patient safety.
  • The interprofessional ARMIN MM program significantly reduced mortality risk.
  • Understanding the role of pharmaceutical interventions (PI) and physician communication is crucial for MM success.

Purpose of the Study:

  • Investigate pharmaceutical interventions (PI) by community pharmacies within the ARMIN program.
  • Assess the types of drug-related problems (DRP) identified and resolved.
  • Evaluate the clinical and economic impact of PIs and physician involvement.

Main Methods:

  • Intervention study with a pre-post design.
  • Observational period of approximately 6 months per patient.
  • Assessed DRPs, PIs, medication changes, clinical/economic impact, and physician communication.

Main Results:

  • 420 DRPs identified initially, 50 during MM; 538 PIs conducted.
  • All patients experienced medication changes; 76% of PIs were successfully implemented.
  • PIs had minor to moderate clinical impact; most had no cost effect. Physician contact occurred in 42.2% of PIs.

Conclusions:

  • ARMIN successfully resolved DRPs through PIs, leading to medication changes and clinical impact.
  • Successful PI implementation highlights the importance of interprofessional collaboration and defined responsibilities.
  • Continuous medication management programs require strong partnerships between community pharmacists and physicians.
Keywords:
Clinical relevanceDrug-related problemsInterprofessional relationsMedication reviewMedication therapy managementPharmaceutical interventionsPharmaceutical services

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