Fog/Edge-Aware State Space Models for Multi-Task Chest X-ray Report Generation and Lesion Detection
IEEE Journal of Biomedical and Health Informatics
|February 25, 2026
Summary
New artificial intelligence (AI) frameworks using state space models (SSMs) improve medical report generation and abnormality detection in chest X-rays. These AI solutions offer enhanced efficiency and accuracy for radiologists.
Area of Science:
- Radiology and Medical Imaging
- Artificial Intelligence in Healthcare
- Computer Vision and Natural Language Processing
Background:
- Current AI systems for radiology face challenges with computational cost and efficiency in modeling long-range dependencies.
- Automating medical report generation and abnormality detection are key areas for AI in radiology.
Purpose of the Study:
- To propose novel state space model (SSM)-based frameworks for enhanced medical report generation and abnormality localization in chest radiographs.
- To address the limitations of existing AI models in terms of computational cost and efficiency.
Main Methods:
- Developed two frameworks: MambaXray-CTL for report generation and MambaXray-MTL for unified report generation and abnormality localization.
- Integrated a lightweight Mamba-based vision encoder with a large language model (LLM) decoder.
- Employed multi-stage contrastive learning to align visual and textual representations.
Main Results:
- MambaXray-CTL achieved state-of-the-art performance on IU X-ray and CheXpertPlus datasets, outperforming Vision Transformer models in efficiency.
- MambaXray-MTL demonstrated effective unified report generation and accurate abnormality localization.
- The proposed methods significantly reduced computational overhead.
Conclusions:
- Combining state space models with contrastive learning provides efficient, interpretable, and deployable AI solutions for chest radiograph analysis.
- The developed frameworks show significant promise in transforming AI applications within diagnostic radiology.


