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Single-Cone vs. Carrier-Based Root Canal Obturation with a Calcium-Silicate-Based Sealer: An In Vitro µ-CT Analysis.

Vincenzo Tosco1, Riccardo Monterubbianesi2, Michele Furlani1

  • 1Department of Life Sciences, Health and Health Professions, Link Campus University, 00165 Rome, Italy.

Biomimetics (Basel, Switzerland)
|February 26, 2026
PubMed
Summary

Carrier-based obturation using calcium-silicate sealers resulted in fewer voids and better filling quality than the single-cone technique. This warm technique offers a denser, more homogeneous root canal filling, especially in coronal and middle thirds.

Keywords:
calcium-silicate-based sealerscarrier-based obturationendodonticsmicro-computed tomographyroot canal obturationsingle-cone technique

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Area of Science:

  • Endodontics
  • Dental Materials Science

Background:

  • Calcium-silicate-based sealers are driving interest in simplified root canal obturation methods like single-cone technique.
  • Warm obturation techniques, such as carrier-based methods, remain the established standard for root canal filling.

Purpose of the Study:

  • To compare the root canal obturation quality between single-cone and carrier-based techniques using the same calcium-silicate-based sealer.
  • To evaluate the impact of obturation technique on void formation and filling homogeneity.

Main Methods:

  • Thirty extracted mandibular molars were prepared using rotary instrumentation.
  • Teeth were randomly assigned to either carrier-based obturation (Soft-Core) or single-cone obturation.
  • All canals were filled with NeoSEALER Flo, a calcium-silicate-based sealer.
  • Micro-computed tomography (micro-CT) was employed for quantitative and qualitative void analysis.

Main Results:

  • Carrier-based obturation showed significantly fewer voids (9.0 ± 5.0) and a smaller total void volume (2.58 ± 0.8 mm³).
  • Single-cone obturation exhibited a higher number of voids (22.0 ± 10.1) and larger void volume (4.71 ± 1.1 mm³).
  • Qualitative analysis revealed denser, more homogeneous fillings with carrier-based methods, while single-cone showed larger voids in coronal and middle thirds.

Conclusions:

  • Carrier-based obturation demonstrated superior overall filling quality compared to the single-cone technique when using calcium-silicate-based sealers.
  • The carrier-based technique resulted in significantly fewer and smaller voids, particularly in the coronal and middle root canal regions.
  • Both techniques achieved a reliable apical seal, but carrier-based obturation offers enhanced homogeneity and reduced voids.