High-Efficiency Continuous Microreactors for Controlled Synthesis of Nanosized Particles of Functional Materials:...

The current state and prospects of microreactor synthesis of functional materials in single- and two-phase flows with a liquid continuous phase are analyzed. Microreactors allow fine control over the size, composition, structure, and properties of synthesized particles in co-precipitation processes. The results obtained by various teams provide grounds to expect fairly extensive capabilities for controlling the processes of nucleation and particle growth in microreactors-by controlling the pH, reagent concentrations, micromixing quality, and residence time in each of the reactor zones-in the nucleation growth zones. The advantages of microreactor synthesis have been demonstrated with a high quality of micromixing in a volume of 0.2-0.5 mL, which ensures the production of nanoparticles without impurities, a stoichiometric ratio of atoms in the product, and limitation of agglomerate growth due to a short residence time (in the order of several milliseconds). The transition to an industrial scale is very easy due to the fairly high productivity of a single microreactor (up to 10 m³/day for suspension, up to 200-300 kg/day for solid phase). Intensive mixing in microreactors with a diameter of 2-4 mm or less, due to Taylor vortices, contributed to the use of two-phase microreactors for the synthesis of both organic and inorganic substances.