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Related Concept Videos

Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

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Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
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Immunodeficiency Diseases01:25

Immunodeficiency Diseases

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Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
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Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
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Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
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Updated: Feb 27, 2026

An In Vitro Model for Measuring Immune Responses to Malaria in the Context of HIV Co-infection
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Helminth Immune Modulation and Invasive Fungal Infections in Sub-Saharan Africa.

Luis Fonte1, Yaxsier de Armas2,3, Héctor R Pérez-Gómez4

  • 1Centro de Investigación, Diagnóstico y Referencia, Instituto de Medicina Tropical "Pedro Kourí", La Habana 11400, Cuba.

Journal of Fungi (Basel, Switzerland)
|February 26, 2026
PubMed
Summary
This summary is machine-generated.

Helminth infections in Sub-Saharan Africa may directly and indirectly increase fungal infections by altering immune responses. A syndemic approach is crucial for managing invasive fungal infections in the region.

Area of Science:

  • * Global Health
  • * Infectious Diseases
  • * Immunology

Background:

Keywords:
HIV infectionInvasive Fungal Infectionshelminth immune modulationsub-Saharan Africatuberculosis

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  • * Sub-Saharan Africa faces high rates of HIV and tuberculosis, major risk factors for fungal infections.
  • * The region also has the highest prevalence of helminth infections, known for their immune-modulating effects.
  • * Helminth infections can impair immune responses to other pathogens like HIV and tuberculosis.