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Colloids03:22

Colloids

21.7K
Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles that are visible to the naked eye or can be seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. On the other hand, a solution is a homogeneous mixture in which no settling occurs and in which the dissolved...
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Colloidal precipitates01:09

Colloidal precipitates

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The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
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Biosynthesis of Lipids01:29

Biosynthesis of Lipids

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Microbial membranes exhibit remarkable diversity in lipid composition, reflecting evolutionary adaptations to various environmental conditions. The three domains of life—Bacteria, Archaea, and Eukarya—synthesize membrane lipids through distinct biosynthetic pathways, leading to fundamental structural differences that impact membrane stability, function, and adaptability.Fatty Acid-Based Lipids in Bacteria and EukaryaBacteria and eukaryotes share a common fatty acid biosynthesis...
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The Colloidal State01:29

The Colloidal State

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The formation of a colloidal system is exemplified by an aqueous solution containing Cl− ions is introduced to another containing Ag+ ions, resulting in the precipitation of solid AgCl as extremely tiny crystals. Instead of settling out as a filterable precipitate, these crystals remain suspended in the liquid, showcasing a colloidal system.A colloidal system involves colloidal particles within the approximate range of 1 to 1000 nm in at least one dimension, dispersed in a medium called...
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Conditions on Early Earth02:06

Conditions on Early Earth

102.3K
Around 4 billion years ago, oceans began to condense on earth while volcanic eruptions released nitrogen, carbon dioxide, methane, ammonia, and hydrogen into the primordial atmosphere. However, organisms with the characteristics of life were not initially present on earth. Scientists have used experimentation to determine how organisms evolved that could grow, reproduce, and maintain an internal environment.
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Theories of Dissolution: The Danckwerts' Model and Interfacial Barrier Model01:09

Theories of Dissolution: The Danckwerts' Model and Interfacial Barrier Model

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Various dissolution theories provide insight into the factors that influence the dissolution rate. Danckwerts' Model suggests that turbulence, rather than a stagnant layer, characterizes the dissolution medium at the solid-liquid interface. In this model, the agitated solvent contains macroscopic packets that move to the interface via eddy currents, facilitating the absorption and delivery of the drug to the bulk solution. The regular replenishment of solvent packets maintains the...
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Related Experiment Video

Updated: Feb 28, 2026

Particle Templated Emulsification enables Microfluidic-Free Droplet Assays
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Particle Templated Emulsification enables Microfluidic-Free Droplet Assays

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Evolution of Pristine Emulsions and Hypothesis Explaining Their Existence.

Andrei Dukhin1, Renliang Xu2, Darrell Velegol3

  • 1Dispersion Technology Inc., 364 Adams Street, Bedford Hills, NY 10507, USA.

International Journal of Molecular Sciences
|February 27, 2026
PubMed
Summary

Pristine emulsions, oil and water without surfactants, show unusual droplet size stabilization. A structured water layer at the interface, explained by a nano-bubble model, prevents unlimited coalescence.

Keywords:
dielectrostatic forcedroplet sizehydrophobic interactionpristine emulsionsurface tensionzeta potential

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Area of Science:

  • Colloid and Interface Science
  • Emulsion Technology
  • Physical Chemistry

Background:

  • Pristine emulsions contain only oil and water, differing from surfactant-stabilized or Pickering emulsions.
  • Understanding the long-term stability of these surfactant-free emulsions is crucial for various applications.

Purpose of the Study:

  • To investigate the long-term evolution of a hexadecane-in-water pristine emulsion.
  • To elucidate the mechanisms behind the unusual droplet size stabilization observed in pristine emulsions.

Main Methods:

  • Preparation and long-term observation of a 4% hexadecane-in-water emulsion.
  • Analysis of droplet size evolution under varying mixing conditions.
  • Application of a theoretical model for nano-bubble stability to explain emulsion behavior.

Main Results:

  • Droplet size in pristine emulsions increases over time, influenced by mixing conditions.
  • Coalescence is limited, reaching a constant droplet size, contrary to typical coalescence behavior.
  • A theoretical model incorporating a structured water layer and dielectrostatic forces accurately predicts observed droplet sizes.

Conclusions:

  • The stability of pristine emulsions can be explained by a model previously used for nano-bubble stability.
  • A structured water layer at the oil-water interface, with dielectrostatic forces, plays a key role in stabilizing droplet size.
  • This model accounts for both the limited coalescence and droplet size stabilization in pristine emulsions.