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Association with Uncontrolled Hypertension in Thoracic Aortic Aneurysm Patients Referred to a Tertiary-Care Center

Laura Ramlawi1,2, Serge Sicouri1, Rhian Touyz3

  • 1Department of Cardiac Surgery Research, Lankenau Institute for Medical Research, Main Line Health, Wynnewood, PA 19096, USA.

Healthcare (Basel, Switzerland)
|February 27, 2026
PubMed

Insights

Blood pressure control is poor in most thoracic aortic aneurysm (TAA) patients, even those in specialized programs. This highlights a critical need for better hypertension management in TAA care.

Area of Science:

  • Cardiology
  • Vascular Surgery
  • Hypertension Management

Background:

  • International guidelines advocate for strict blood pressure (BP) control in thoracic aortic aneurysm (TAA) patients.
  • Elevated BP in TAA is linked to accelerated aneurysm growth, aortic dissection, and rupture.
  • This study investigates BP control within a specialized TAA management program.

Purpose of the Study:

  • To assess the prevalence and control of hypertension in TAA patients referred to a tertiary aortic center.
  • To identify factors associated with BP control in this high-risk population.

Main Methods:

  • Retrospective analysis of 3525 TAA patients managed at the Lankenau Aortic Surgical Program (2021-2024).
  • BP measurements were standardized using automated sphygmomanometers.
  • Hypertension staging followed the 2023 European Society of Hypertension (ESH) guidelines.

Main Results:

  • Over half (54.2%) of TAA patients presented with above-target BP.
  • Stage 1 hypertension (BP > 140/90) was most common (53.4%), followed by Stage 2 (12.6%) and Stage 3 (1.8%).
  • No significant demographic disparities (race, income, home value) were found, though higher education levels showed a trend toward lower BP.

Conclusions:

  • Hypertension is highly prevalent and inadequately managed in TAA patients, even in specialized settings.
  • Current risk factor management requires enhancement to improve outcomes for TAA patients.
  • Further research into optimizing BP control strategies for TAA is warranted.

Keywords:
blood pressuredemographichypertensionthoracic aortic aneurysmuncontrolled

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