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Related Experiment Video

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Biopsy Needle Integrated with Rotational Oblique Spectral Ultrasound (ROSUS) Imaging.

Benjamin C Kreager1, Wei-Yi Chang2, Jian Tian3

  • 1Department of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC 27695, USA.

Sensors (Basel, Switzerland)
|February 27, 2026
PubMed
Summary

A new ultrasound system improves blood vessel visualization during biopsies, reducing risks like hemorrhage. This technology enhances needle guidance for safer, more accurate cancer diagnosis procedures.

Keywords:
blood vessel detectionfine needle aspirationhigh-frequency ultrasoundsingle-element ultrasoundspectral ultrasound imaging

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Area of Science:

  • Medical Imaging
  • Biotechnology
  • Surgical Technology

Background:

  • Biopsy procedures are crucial for cancer diagnosis but carry risks of blood vessel puncture and hemorrhage.
  • Current imaging guidance lacks sufficient vascular contrast, complicating vessel avoidance during needle insertion.

Purpose of the Study:

  • To develop and evaluate a novel ultrasound imaging system for enhanced vessel detection and needle guidance during biopsy.
  • To improve the safety and accuracy of needle-based biopsy procedures.

Main Methods:

  • Development of a rotational oblique spectral ultrasound (ROSUS) imaging system integrating a high-frequency transducer at the needle tip.
  • Implementation of synchronized rotational-axial scanning and multifrequency signal ratio (MFSR) processing.
  • Evaluation of volumetric imaging capabilities and blood-tissue contrast.

Main Results:

  • ROSUS achieved over 1.2 dB blood-tissue contrast ratio improvement compared to conventional B-mode.
  • Maintained high spatial resolution (85 µm axial, 424 µm lateral).
  • Demonstrated improved vessel and tissue differentiation using frequency-domain spectral processing.

Conclusions:

  • The ROSUS system offers enhanced visualization for safer biopsy procedures.
  • Frequency-domain spectral processing improves vascular differentiation in ultrasound imaging.
  • An 18-gauge needle-integrated platform can lead to more accurate and safer biopsies.