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Updated: Feb 28, 2026

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD
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Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD

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Neuroprotective Marine Bioactives in Paediatric ADHD: A Focused Review on Therapeutic Potential

Benu Chaudhary1, Preeti Arya2, Praveen Kumar3

  • 1Department of Pharmacy, Panipat Institute of Engineering and Technology, Panipat, Haryana, India.

CNS & Neurological Disorders Drug Targets
|February 27, 2026
PubMed

Insights

Marine bioactives show promise for managing Attention-Deficit/Hyperactivity Disorder (ADHD) in children. These natural compounds offer potential neuroprotective benefits, supporting cognitive function and neurodevelopment as alternatives to conventional treatments.

Area of Science:

  • Neuroscience
  • Marine Biology
  • Pediatrics

Background:

  • Attention-Deficit/Hyperactivity Disorder (ADHD) is a prevalent neurodevelopmental condition in children.
  • Symptoms include inattention, hyperactivity, and impulsivity, impacting cognitive function and development.
  • Marine-derived bioactive compounds are being explored for their potential in supporting neurodevelopment and managing ADHD symptoms.

Purpose of the Study:

  • To review the potential of marine-derived bioactive compounds for managing ADHD in children.
  • To analyze compounds with therapeutic value for ADHD management.
  • To highlight natural alternatives to conventional ADHD treatments.

Main Methods:

  • Systematic literature search of databases including PubMed, Scopus, Web of Science, and ClinicalTrials.gov.
  • Inclusion of human clinical trials and preclinical research up to July 2025.
  • Focus on studies related to marine bioactives and ADHD in children or neurodevelopmental outcomes.

Main Results:

  • Marine sources contain neuroprotective agents like Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA), vital for brain development.
  • Compounds such as Klamin® (from Aphanizomenon flos-aquae) show potential for attention regulation via monoamine oxidase B inhibition.
  • Marine peptides and polysaccharides exhibit anti-inflammatory and neuroregenerative properties relevant to ADHD.

Conclusions:

  • Marine bioactives offer a novel, natural avenue for ADHD management through nutritional interventions.
  • These compounds present potentially safer alternatives to traditional pharmacological treatments.
  • Further clinical research is essential to confirm efficacy, optimal dosing, and long-term safety.
Abstract

Keywords:
Neuroprotectionanti-inflammatoryantioxidantattention-deficit disorderhyperactivity disordermarine bioactivesneuroregenerative properties.

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