Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Cell Death01:30

Overview of Cell Death

10.6K
Cell death is an essential process where the body gets rid of old or damaged cells. Cell proliferation and death need to be balanced, as an imbalance between the two may lead to cancer or autoimmune diseases.
Cell death was observed in the early 19th century, but there was no experimental evidence to prove it. In 1842, Carl Vogt first discovered cell death in a metamorphic toad; however, it was not termed ‘cell death.’ Scientists discovered different cell death pathways only in the...
10.6K
Apoptosis01:30

Apoptosis

16.2K
Apoptosis is a combination of two Greek words, 'apo' and 'ptosis,' meaning separation and falling off, respectively. Hippocrates used this word to describe gangrene, which was caused due to bandaging of fractured bones. Apoptosis was distinguished from necrosis in 1970 when John Kerr reported observations of morphological changes occurring during apoptosis. During one experiment, he observed that the disruption of blood supply to the liver tissue resulted in a size...
16.2K
Necrosis01:16

Necrosis

6.9K
Necrosis is considered as an “accidental” or unexpected form of cell death that ends in cell lysis. The first noticeable mention of “necrosis” was in 1859 when Rudolf Virchow used this term to describe advanced tissue breakdown in his compilation titled “Cell Pathology”.
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become...
6.9K
Autophagic Cell Death01:18

Autophagic Cell Death

4.8K
Christian de Duve discovered “autophagy,” a process in which cellular components are engulfed by membrane-bound organelles called autophagosomes. The autophagosomes then fuse with lysosomes to digest the enclosed contents. Autophagy is generally activated in cells to prevent cell death. However, cell death is triggered when the damage is beyond repair.
Autophagy and Apoptosis
Autophagy can activate apoptosis. In normal conditions, the autophagy activating protein Beclin-1 and...
4.8K
The Extrinsic Apoptotic Pathway01:17

The Extrinsic Apoptotic Pathway

9.0K
The extrinsic apoptotic pathway is initiated when extracellular death-inducing signals, such as specific cytokines, activate the death receptors expressed on the cell surface. The immune cells involved in this pathway are natural killer cells (NK cells) and cytotoxic T-lymphocytes. NK cells are critical in innate immune response, while cytotoxic T-lymphocytes are associated with adaptive immune response. These cells recognize specific receptors expressed on the altered cells and activate...
9.0K
Morphogenesis02:19

Morphogenesis

30.6K
Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
30.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Shedding light on plant proteolysis: genetically encoded fluorescent sensors as tools for profiling protease activities.

The Plant cell·2026
Same author

Root hair lifespan is antagonistically controlled by autophagy and programmed cell death.

Nature plants·2026
Same author

KIL transcription factors facilitate embryo growth in maize by promoting endosperm elimination via lytic cell death.

The Plant cell·2025
Same author

Hygrometrically controlled programmed cell death drives anther opening and pollen release.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Fight to survive: Marchantia synthesizes newly identified metabolites in response to wounding.

Plant physiology·2025
Same author

Root cap cell corpse clearance limits microbial colonization in <i>Arabidopsis thaliana</i>.

eLife·2024
Same journal

Expanding the C. elegans toolkit with gonad explants.

Development (Cambridge, England)·2026
Same journal

Nuclear Factor Y controls nutrient-adaptive epithelial growth by regulating mTOR in the Drosophila midgut.

Development (Cambridge, England)·2026
Same journal

Primordial germ cells differentially contribute to the germline in zebrafish.

Development (Cambridge, England)·2026
Same journal

Dissecting planar and vertical organiser signals in early chick neural development.

Development (Cambridge, England)·2026
Same journal

Real-time transcriptomic profiling of hPSC-derived cartilage during development identifies a key role for the extracellular matrix in homeostasis and protection.

Development (Cambridge, England)·2026
Same journal

In preprints - housekeeping the housekeeping genes.

Development (Cambridge, England)·2026
See all related articles

Related Experiment Video

Updated: Feb 28, 2026

Author Spotlight: A Streamlined Approach to Studying Cell Death Initiation in Hypersensitive Response
06:06

Author Spotlight: A Streamlined Approach to Studying Cell Death Initiation in Hypersensitive Response

Published on: November 10, 2023

2.1K

Programmed cell death during plant development.

Eugenia Pitsili1,2, Moritz K Nowack1,2

  • 1Ghent University, Department of Plant Biotechnology and Bioinformatics, Technologiepark 71, 9052 Ghent, Belgium.

Development (Cambridge, England)
|February 27, 2026
PubMed
Summary
This summary is machine-generated.

Programmed cell death (PCD) is crucial for plant development and immunity. Recent advances in technology and plant models are accelerating discoveries in plant PCD molecular regulation.

Keywords:
DPCDPlant developmentPlantsProgrammed cell death

More Related Videos

A &#946;-glucuronidase GUS Based Cell Death Assay
07:35

A β-glucuronidase GUS Based Cell Death Assay

Published on: May 6, 2011

28.8K
Author Spotlight: THP-1 Macrophage Response to LPS/ATP &#8212; Unveiling the Pyroptosis, Apoptosis, and Necroptosis Spectrum
06:12

Author Spotlight: THP-1 Macrophage Response to LPS/ATP — Unveiling the Pyroptosis, Apoptosis, and Necroptosis Spectrum

Published on: May 3, 2024

3.5K

Related Experiment Videos

Last Updated: Feb 28, 2026

Author Spotlight: A Streamlined Approach to Studying Cell Death Initiation in Hypersensitive Response
06:06

Author Spotlight: A Streamlined Approach to Studying Cell Death Initiation in Hypersensitive Response

Published on: November 10, 2023

2.1K
A &#946;-glucuronidase GUS Based Cell Death Assay
07:35

A β-glucuronidase GUS Based Cell Death Assay

Published on: May 6, 2011

28.8K
Author Spotlight: THP-1 Macrophage Response to LPS/ATP &#8212; Unveiling the Pyroptosis, Apoptosis, and Necroptosis Spectrum
06:12

Author Spotlight: THP-1 Macrophage Response to LPS/ATP — Unveiling the Pyroptosis, Apoptosis, and Necroptosis Spectrum

Published on: May 3, 2024

3.5K

Area of Science:

  • Plant Biology
  • Cellular Biology
  • Molecular Biology

Background:

  • Programmed cell death (PCD) is essential for multicellular organisms, regulating development and immunity.
  • While extensively studied in animals, plant PCD research is a rapidly advancing field.
  • Understanding plant PCD is critical for various biological processes.

Purpose of the Study:

  • To highlight the functional roles of PCD in plant development.
  • To discuss the molecular and cellular mechanisms of plant PCD.
  • To outline historical challenges and emerging innovations in plant PCD research.

Main Methods:

  • Literature review of existing research on plant PCD.
  • Analysis of molecular and cellular frameworks governing PCD in plants.
  • Identification of technological innovations and model systems driving discoveries.

Main Results:

  • PCD plays integral roles in various aspects of plant development.
  • Established molecular and cellular pathways regulate PCD initiation and execution in plants.
  • Overcoming historical challenges is paving the way for new discoveries.

Conclusions:

  • Plant PCD is a complex and vital process with diverse developmental roles.
  • Current technological advancements and model systems are crucial for future plant PCD research.
  • Continued investigation into plant PCD mechanisms will yield significant biological insights.