Application of PLCL as a biodegradable polymer in biomedical engineering

Area of Science:

• Biomaterials Science
• Polymer Chemistry
• Biomedical Engineering

Background:

• Poly (L-lactide-co-ε-caprolactone) (PLCL) is a novel biocompatible polymer.
• A comprehensive summary of its applications is needed.

Purpose of the Study:

• To review the physicochemical properties and influencing factors of PLCL.
• To consolidate PLCL processing and preparation methods for biomedical applications.
• To systematically overview current PLCL applications and modification strategies.

Main Methods:

• Literature review of PLCL properties, processing, applications, and modifications.
• Systematic consolidation of existing research data.

Main Results:

• PLCL exhibits exceptional biocompatibility.
• Key applications include wound healing, cardiovascular stents, nerve repair, osteochondral tissue engineering, drug delivery, and screening.
• Modification strategies can enhance PLCL performance.

Conclusions:

• PLCL is a versatile polymer with significant potential in various biomedical fields.
• This review provides insights for future PLCL research and development.