Related Experiment Video
Updated: Feb 28, 2026

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
Published on: April 6, 2017
Effect of Replacing Inhalation Devices on Medication Adherence.
Yusuf Aydemir1, Sahinur Aycan Alkan2, Damla Serçe Unat3
1Department of Pulmonology, Faculty of Medicine, Sakarya University, Sakarya, Türkiye.
Inhaler device replacement can improve patient skills and satisfaction, especially for those with inadequate training. While not always recommended, it offers a chance for new education and better adherence in respiratory disease management.
Area of Science:
- Respiratory Medicine
- Pharmacology
- Patient Adherence
Background:
- Inhaler device use is critical for treating respiratory diseases like COPD and asthma.
- Patient skill and adherence are paramount for effective inhaler therapy.
- Frequent inhaler device replacement is generally discouraged due to potential adherence disruption.
Purpose of the Study:
- To investigate the frequency and reasons for inhaler device replacement.
- To assess inhaler adherence and usage skills following device replacement.
- To evaluate patient satisfaction with new inhaler devices.
Main Methods:
- Study included 260 patients with chronic respiratory diseases (COPD, asthma) on inhaler treatment for over 1 year.
- Data collected on inhaler device satisfaction, skill level, prior training, and device replacement history.
- Patients' device usage skills and satisfaction were assessed post-replacement.
Main Results:
- Device replacement occurred in 60.8% of patients; 87.3% were satisfied with new devices.
- Primary reasons for replacement included patient request (34.2%) and formulation changes (17.1%).
- Device usage skills improved significantly in the replaced-device group (p=0.04), with 15.4% reporting insufficient prior training.
Conclusions:
- Inhaler device replacement can be beneficial for patients dissatisfied with their current device.
- Replacement offers a valuable opportunity for retraining, particularly for patients with inadequate initial education.
- While not routine, strategic device replacement may enhance patient outcomes in respiratory care.
Related Concept Videos
Inhaled Medications
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Antiasthma Drugs: β2-Adrenoceptor Agonists
One class of bronchodilators includes β2-adrenoceptor agonists. These agents target the β2-adrenoceptors located on bronchial smooth muscle cells. By stimulating these receptors, β2-agonists induce...
Drugs Used in Lower Respiratory Disorders: Overview
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Chronic Obstructive Pulmonary Disease-V: Management
Smoking Cessation
COPD: Management Using Bronchodilators and Corticosteroids

