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Updated: Mar 1, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

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Genetic resonance in the p53 signaling network

Mathias S Heltberg1, Alba Jimenez2, Galit Lahav2

  • 1Niels Bohr Institute, University of Copenhagen, 2100 Copenhagen, Denmark.

Cell Systems
|February 27, 2026
PubMed
Summary

This study reveals resonance, a phenomenon previously known in physics, also occurs in gene regulatory networks. The tumor suppressor p53 exhibits resonance, amplifying its response to DNA damage and potentially activating specific genes.

Keywords:
cellular regulationdamped oscillationsenhanced transcriptiongenetic oscillationsnon-linear resonancep53 networkresonanceselective gene expressionsignal amplification

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