Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

613
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
613
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

448
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
448
Urinary Tract Calculi VI: Surgical Management01:25

Urinary Tract Calculi VI: Surgical Management

687
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
687
Imaging Studies for Cardiovascular System III: X-Ray01:20

Imaging Studies for Cardiovascular System III: X-Ray

541
The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
541
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

345
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
345

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Heart Failure Pharmacotherapy Across the TAVR Continuum.

Journal of cardiac failure·2026
Same author

Managing PA-IVS With RV-Coronary Connections Using TEE.

JACC. Case reports·2026
Same author

Serial OCT-based coronary physiology and plaque composition in vessels with nonobstructive coronary lesions following intensive lipid-lowering therapy: YELLOW III sub-study.

Atherosclerosis·2026
Same author

TAVR in a Small Surgical Bioprosthesis With a Kinked Aortic Graft Using an Intra-Annular Self-Expanding Valve.

JACC. Case reports·2026
Same author

Sex differences in reverse remodeling after transcatheter aortic valve replacement in low-flow aortic stenosis.

The Journal of invasive cardiology·2026
Same author

Intra-coronary imaging and transcriptomics of calcified nodules before and after intensive lipid-lowering therapy: a YELLOW III substudy.

European heart journal. Imaging methods and practice·2026

Related Experiment Video

Updated: Mar 2, 2026

Author Spotlight: Advancing Cardiovascular Imaging - Introducing the Spatially Weighted Calcium Score for Early Disease Detection
06:57

Author Spotlight: Advancing Cardiovascular Imaging - Introducing the Spatially Weighted Calcium Score for Early Disease Detection

Published on: September 22, 2023

1.5K

Cracking Coronary Calcium With Intravascular Lithotripsy: A Review.

Sachin Kumar1, Robert Trenschel1, Tushar Mishra1

  • 1Icahn School of Medicine at Mount Sinai, The Zena and Michael A. Wiener Cardiovascular Institute, New York, New York.

The American Journal of Cardiology
|February 28, 2026
PubMed
Summary
This summary is machine-generated.

Intravascular lithotripsy (IVL) effectively fractures calcified coronary lesions (CCL) during stenting, improving outcomes. While safe and feasible across various lesion types, further comparative data is needed to fully define its role.

Keywords:
calcified coronary lesionsintravascular imagingintravascular lithotripsypercutaneous coronary interventionplaque modification

More Related Videos

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
04:40

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans

Published on: August 28, 2018

16.2K
A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
11:30

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro

Published on: June 2, 2022

2.6K

Related Experiment Videos

Last Updated: Mar 2, 2026

Author Spotlight: Advancing Cardiovascular Imaging - Introducing the Spatially Weighted Calcium Score for Early Disease Detection
06:57

Author Spotlight: Advancing Cardiovascular Imaging - Introducing the Spatially Weighted Calcium Score for Early Disease Detection

Published on: September 22, 2023

1.5K
Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
04:40

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans

Published on: August 28, 2018

16.2K
A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
11:30

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro

Published on: June 2, 2022

2.6K

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Medical Device Technology

Background:

  • Heavily calcified coronary lesions (CCL) pose significant challenges during percutaneous coronary intervention, often leading to incomplete stent expansion and poorer long-term results.
  • Traditional calcium modification methods carry procedural risks and may be insufficient for complex calcifications.

Purpose of the Study:

  • To review the evidence supporting intravascular lithotripsy (IVL) as a safe and effective strategy for modifying calcified coronary lesions.
  • To evaluate IVL's performance across diverse lesion morphologies and compare it with other calcium modification techniques.

Main Methods:

  • Systematic review of pivotal trials and real-world data on IVL for calcified coronary lesions.
  • Analysis of IVL safety, feasibility, and effectiveness in various lesion subsets, including eccentric calcium and left main disease.
  • Comparison of IVL with conventional calcium modification modalities.

Main Results:

  • Intravascular lithotripsy (IVL) demonstrated safety and feasibility in modifying calcified coronary lesions (CCL), including complex cases.
  • IVL effectively fractures calcium, minimizing vessel trauma compared to some conventional methods.
  • Evidence supports IVL's utility in lesion preparation for percutaneous coronary intervention.

Conclusions:

  • Intravascular lithotripsy (IVL) is a valuable tool for managing calcified coronary lesions (CCL), offering a safe and effective approach to lesion preparation.
  • Limitations include a lack of extensive randomized comparative data and cost considerations.
  • Ongoing trials will further elucidate IVL's role in contemporary interventional cardiology practice.