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Navigating Melatonin Safety: Fact, Fiction, and Confounders
Alessandro Colitta1, Francy Cruz-Sanabria2, Simone Bruno3
1Department of Clinical and Experimental Medicine, Neurology Unit, University of Pisa, Pisa, Italy.
None:
As a chronobiotic with sleep-promoting properties, melatonin is frequently recommended by sleep medicine practitioners and widely available as an over-the-counter drug. Recently, two publications questioned melatonin safety profile in insomnia patients, with one of these receiving vast media coverage and noticeable resonance among the general public. This letter to the Editor critically evaluates such research, offering a broader contextualization within the existing body of literature about melatonin safety and insomnia-related health outcomes.
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