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Updated: Mar 3, 2026
Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
Published on: January 5, 2024
Repeated virtual reality sessions in fibromyalgia: a prospective observational study
Jean-Marie Amodeo1, Frederic Berthier2, Cindy Biehlmann1
1Pain Management, Centre Hospitalier Princesse Grace, Monaco, Principality of Monaco.
Aims:
Fibromyalgia (FM) is a chronic pain syndrome with limited effective treatments. This study evaluated virtual reality (VR) as an adjunct therapy.
Methods:
Participants used the HealthyMind program delivered via a Pico G2 4K Enterprise headset in eight supervised, seated 20-minute sessions over four weeks, featuring nature relaxation, guided imagery, and meditation. Primary outcome was Pain Numerical Rating Scale (NRS) at one month (M1); secondary outcomes included PCS, PSEQ, and HADS.
Results:
Fifty participants completed baseline and M1 assessments. Pain significantly decreased from 6.8 ± 1.5 to 5.8 ± 1.9 (-14.8%, p < 0.001; effect size = 0.56). Significant improvements were observed in catastrophizing, self-efficacy, anxiety, and depression.
Conclusion:
Repeated HealthyMind VR use was associated with reduced pain and improved psychological outcomes in FM patients.
Clinical Trial Registration:
www.clinicaltrials.gov identifier is (NCT05567861).
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