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Related Concept Videos

Blinding01:11

Blinding

Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.

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Cervical Rotation-Traction Manipulation of Different Treatment Frequency in Cervical Radiculopathy: Study Protocol

Tianxiao Feng1, Xu Wang1, Kai Sun1,2

  • 1Orthopedics and Traumatology Department, Wangjing Hospital of China Academy of Chinese Medical Sciences, Beijing, 100102, People's Republic of China.

Journal of Pain Research
|March 2, 2026
PubMed
Summary

This study compares three sessions per week of cervical rotation-traction manipulation (CRTM) to one session per week and cervical traction alone for cervical radiculopathy (CR). It aims to find the optimal CRTM frequency for pain and dysfunction relief.

Keywords:
cervical radiculopathycervical rotation-traction manipulationrandomized controlled trialstudy protocoltreatment frequency

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Area of Science:

  • Orthopedics
  • Manual Therapy
  • Traditional Chinese Medicine

Background:

  • Cervical radiculopathy (CR) significantly impacts patients' quality of life.
  • Cervical rotation-traction manipulation (CRTM), a Traditional Chinese Medicine technique, shows promise for CR symptom relief.
  • Optimal CRTM treatment frequency for CR requires further investigation through randomized controlled trials (RCTs).

Purpose of the Study:

  • To assess the effectiveness and safety of three sessions per week of CRTM (TSWM) versus one session per week of CRTM (OSWM) and cervical traction (CT) for CR.
  • To determine the optimal treatment frequency for CRTM in managing CR symptoms.
  • To provide a reference for exploring dose-response relationships in manual therapy.

Main Methods:

  • A multicenter, three-arm, prospective randomized controlled trial (RCT) involving four hospitals in China.
  • Participants (1:1:1 ratio) allocated to TSWM, OSWM, or CT groups, receiving 4-week treatment and 16-week follow-up.
  • Primary outcome: Visual Analog Scale (VAS) for neck and arm pain at week 4. Secondary outcomes include NDI, SF-12, cost, recurrence, and ETCS. Adverse events monitored.

Main Results:

  • This section is to be filled once the study is completed and results are available.

Conclusions:

  • This clinical study is expected to evaluate the optimal frequency of CRTM for cervical radiculopathy.
  • Findings will serve as a reference for investigating the dose-response relationship of manual therapy for CR.