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Clinical assessment of Psoriatic Arthritis
James Kimpton1, William Tillett1
1University of Bath, Department of Life Sciences, Centre for Therapeutic Innovation, Bath, UK; Royal National Hospital for Rheumatic Diseases, Royal United Hospitals Bath NHS Foundation Trust, Bath, UK.
Abstract:
Psoriatic arthritis (PsA) is a heterogeneous inflammatory condition associated with multiple comorbidities and can impact on quality of life. Comprehensive assessment is integral to the treat-to-target strategy yet evaluating multiple disease domains to quantify disease burden and inform treatment selection remains challenging in routine practice and research settings. In the absence of reliable biomarkers, clinical examination remains central to assessment, but its limitations necessitate a multidimensional approach incorporating patient-reported outcome measures, laboratory tests, and imaging. The GRAPPA-OMERACT working group has developed a core domain set and continues to standardise outcome measure instruments. Composite outcome measures offer a practical solution for capturing disease across multiple domains. However, further work is needed to ensure these measures are feasible and practical for routine clinical use. Emerging digital health technologies offer opportunities to enhance remote monitoring and longitudinal assessment. This chapter reviews key PsA domains and relevant outcome measures in clinical and research contexts.
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