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Acute Generalized Exanthematous Pustulosis in a Neonate Following Hepatitis B Vaccination: A Case Report
Tung Viet Cao1,2, Thuy Minh Ha3, Anh Thi Van Nguyen1
1Vietnam University of Traditional Medicine, Hanoi, Vietnam.
Sage Open Pediatrics
|March 3, 2026
Summary
Acute generalized exanthematous pustulosis (AGEP) in neonates is rare but can be vaccine-induced. This case highlights a newborn developing AGEP after a hepatitis B vaccine, resolving with topical treatment.
Area of Science:
- Neonatal dermatology
- Vaccine adverse reactions
- Cutaneous immunology
Background:
- Acute generalized exanthematous pustulosis (AGEP) is a rare, severe cutaneous adverse reaction, typically drug-induced.
- Vaccine-associated AGEP is uncommon in neonates.
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